6 Best Areas to Stay in Florence, Italy

Situated about 270 km (168 miles) northwest of Rome, Florence, or as the Italians call it, Firenze is a city of wonders. Florence is the capital city of the Tuscany region and is located in central Italy on either side of the Arno River.

It is a picturesque city adorned with hills, bountiful orchards, and vineyards, and home to some of the world’s finest wine, as well as the leading fashion brand Gucci.

Florence is definitely one of the most beautiful places in Italy, however, if you’re planning to visit Florence for the first time, you might feel a little bit lost about where to stay in Florence.

However small, Florence has several distinct areas that vary in culture, flavor, and nightlife. In this article, I have put together a list of the best areas to stay in Florence with pros-cons and hotel recommendations for each area.  Let’s get into it!

*Disclosure: This post contains a few affiliate links, which means I may receive a small commission, at no cost to you, if you make a purchase through my link.*

Overview of the Where to Stay in Florence

Florence is a relatively small city (that’s why 2 days in Florence is enough to see all the main attractions), and its center, also called the medieval or the Renaissance heart, is still compact.

Florence’s center lies between the Duomo in the north and the Arno River in the south. To the east of the city center are the Santa Croce and Sant’Ambrogio areas, while the Santa Maria Novella area is towards the west.

North of the city center is housed by San Lorenzo and San Marco, whereas Santo Spirito and Piazzale Michelangelo tend towards the south. You will get a pretty good idea of these different areas when you look at the city map below.

If you are wondering where to stay in Florence, this article will help you understand each neighborhood’s unique personality.

Here’s a quick overview of the best areas to stay in Florence with hotel recommendations for each area.

Area	Recommended Hotel
Piazza della Signoria or Duomo (first-time visitors, sightseeing)	Relais Tosinghi
Santa Maria Novella (family-friendly, budget-friendly)	Hotel Croce Di Malta
San Lorenzo and San Marco (museums, budget friendly)	Arte’ Boutique Hotel
Santa Croce (vibrant nightlife, bars, restaurants)	Eurostars Florence Boutique
San Frediano and Santo Spirito (local vibes, affordable nightlife)	Hotel Pitti Palace al Ponte Vecchio
San Niccolo & Piazzale Michelangelo (city views, museums)	Art Hotel Villa Agape

Map of the Best Areas to Stay in Florence

How to use this map: This map is fully interactive, so you can move around, zoom in/zoom out, and click on the icons. If you want to see a larger map, click on the bracket in the upper right corner. To see more details and the different layers, click on the tab in the upper left corner. If you want to save it for later, click on the star icon next to the name of the map. Then simply open Google Maps either on your desktop or phone, go to ‘Saved’/’Maps’, and open the map whenever you need it.

Where to Stay in Florence: Best Areas & Hotels

1. Piazza della Signoria or Duomo

Piazza Della Signoria is the heart of Florence. This area is in the city’s center and is one of the best neighborhoods to stay in Florence for museums and sightseeing.

All the major sights are either concentrated in this area or are located within walking distance. In Piazza Della Signoria, you will find narrow streets dotted with trendy cafes and high-street brand boutiques.

The area’s iconic landmarks include the Cathedral of Santa Maria del Fiore with the Duomo and Giotto’s Campanile, the Bargello Museum, and the Uffizi Gallery. Climbing on top of the Duomo is undoubtedly one of the best things to do in Florence, where you can get incredible views of the entire city!

You can also walk through the fantastic collection of Italian Renaissance sculptures at the Bargello Museum.

Piazza della Signoria is a heaven for food lovers and is one of the best areas to stay in Florence for foodies – you can grab a sandwich at I’ Girone De’ Ghiotti, savor a home-made pizza at Gustarium, and sip a cappuccino at Il Vinile.

2. Santa Maria Novella

Located on the north side of the Arno River, Santa Maria Novella is home to Florence’s main train station and is one of the city’s most well-connected areas. This neighborhood is just 15 minutes walking distance from Duomo, the city center.

Although living near the train station is very convenient, I advise you to avoid the nearby noisy and chaotic area and move further towards the more pleasant and charming neighborhood hub. If you are traveling with your family, Santa Maria Novella is hands down the best area to stay in Florence.

In this area, you will find the Church of Santa Maria Novella, which is the region’s Dominican church and the city’s first great basilica. This is also the area where you will find Parco delle Cascine, Florence’s historical park, which is perfect for family outings.

Also, visit the Chiesa di Ognissanti, an important Italian Renaissance church where Botticelli is buried, as well as the Museo Novecento, where you can browse through interesting works of modern art. Another gem is the Santa Maria Novella Pharmacy which is the world’s oldest pharmacy. 

3. San Lorenzo and San Marco

Located north of Duomo, San Lorenzo and San Marco are neighborhoods stuffed with historic palazzis, museums, and churches. You will find many budget accommodations in these areas, making it one of the best areas to stay in Florence.

San Marco houses the San Marco church, Museo di San Marco, and the Accademia Gallery, which is home to Michelangelo’s famous David statue. In San Marco, you could also visit the Basilica della Santissima Annunziata and explore the Museo degli Innocenti, which houses a wonderful collection of Tuscan art.

On the other hand, San Lorenzo houses the Basilica of San Lorenzo and the Medici chapels. San Lorenzo is a hub for foodies where you can get to savor authentic Tuscan cuisine. You can never experience Italy at its finest if you haven’t tried a plate of pasta or a pizza at the Trattoria Pizzeria San Gallo!

4. Santa Croce

Located to the east of Florence’s center, Santa Croce is a neighborhood known for good food, local flavor, and amazing nightlife. Home to the majestic Basilica of Santa Croce, this area has a vibrant culture.

The chapel at the Basilica serves as a resting place for some prominent Italian artists, including Michelangelo and Galileo. 

Santa Croce is packed with clubs, bars, restaurants, and cafes that attract both locals and tourists. It is the best area to stay in Florence for young people looking for parties and fun.

The neighborhood also houses several flea markets and authentic Tuscan shops. You can also find the Florence National Central Library, Church of Saint Ambrose, and various other attractions in the vicinity.

5. San Frediano and Santo Spirito

San Frediano and Santo Spirito are great neighborhoods located in the Oltrarno district, south of the Arno River in Florence. If you are looking for a quiet offbeat place to stay in the city, then these are the best areas to stay in Florence for you.

These areas are filled with boutique shops, small cafes, fine dining restaurants, and artisan workshops holding up centuries-old traditions of handicrafts.

These Florence neighborhoods house Palazzo Pitti – the Renaissance palace, and the Boboli Gardens – a historical garden. You can marvel at the elaborate interiors designed by Brunelleschi inside the Basilica di Santo Spirito.

Santa Maria del Carmine is also an important landmark that is the best example of Gothic architecture. You can take night strolls on the Ponte Vecchio bridge, shop for artifacts at the Santo Spirito flea market, and grab a drink at one of the bars or bistros.

6. San Niccolo & Piazzale Michelangelo

San Niccolò lies along the river Arno towards its southern banks, whereas Piazzale Michelangelo is located on the hills south of San Niccolò.

Both these areas offer incredible views of the city, making them amongst the best neighborhoods to stay in Florence for honeymooners and romance seekers. The areas also suit travelers of all budgets and are quieter than the rest of the city’s places. 

You can explore the Gate of San Niccolò, located just below Piazzale Michelangelo, and admire Florence’s spectacular views. Some of the nicest workshops with unique pieces of art are lined along the streets of San Niccolò.

It’s also home to fantastic museums like Museo Bardini and Museo Casa Siviero. Climb to the best vantage points of Piazzale Michelangelo to take in Florence’s views. This area is best for watching the sunset.